Lab barbecue, August 2021

Lab barbecue, August 2021

Principal Investigator

Tobias W. Giessen, PhD (CV)
Assistant Professor of Biological Chemistry
Affiliate Faculty, Department of Biomedical Engineering
Faculty Member, Program in Chemical Biology
Faculty Member, Cellular & Molecular Biology Program
Faculty Member, Program in Biomedical Sciences

E-mail: tgiessen@umich.edu

Education:
M.Sc. in Chemistry, Philipps-University Marburg, Germany
Ph.D. in Biochemistry, Philipps-University Marburg, Germany
Postdoc, Harvard Medical School

Tobias grew up in Germany and attended Philipps-University Marburg in Hesse. He spent two semester at Imperial College London, UK in the group of Alan Armstrong working on synthetic organic chemistry before graduating with a M.Sc. His Ph.D. training was with Mohamed A. Marahiel where he focused on the discovery and enzymology of novel antibiotics. He completed his postdoctoral training with Pamela A. Silver working on the discovery and engineering of microbial protein organelles before joining UM in 2019.

Postdoctoral Research Fellows

Michael Andreas, PhD

Michael Andreas, PhD

Mike is from Indiana and received his undergraduate degree from Indiana University-Bloomington. He is currently finishing his PhD in Biochemistry from the University of Wisconsin-Madison in Ivan Rayment’s lab where he is studying the cardiac myosin rod and synthetic myosin thick filaments by electron microscopy and x-ray crystallography. He is interested in using cryo-EM to study large macromolecular assemblies, as well as using protein engineering to produce proteins with novel and practical functions.

 

Graduate Students

Robert Benisch(Program in Chemical Biology)

Robert Benisch

(Program in Chemical Biology)

Robert is from Germany and did his Bachelor in Liberal Arts and Sciences at Erasmus University College in Rotterdam, the Netherlands. He received broad training both in cell biology during his Bachelor as well as structural biology during his gap-year interning at Surrozen in the San Francisco Bay. He is broadly interested in synthetic biology and its applications in bioenergy, food & agriculture, and green chemistry, to build a more sustainable future.

 
Cassie Dutcher(PIBS Biological Chemistry)

Cassie Dutcher

(PIBS Biological Chemistry)

Cassie is from Michigan and graduated with a BS in Biochemistry from Michigan State University. While she was an undergraduate, she worked in Cheryl Kerfeld’s lab engineering bacterial microcompartment shells. She is broadly interested in encapsulin discovery, characterization and engineering.

 
Seokmu Kwon(Chemical Engineering)

Seokmu Kwon

(Chemical Engineering)

Kwon is from South Korea and graduated with a BS in Chemical Engineering from POSTECH (Pohang University of Science and Technology) in South Korea. He trained in cellular engineering while doing research related to metabolic engineering during his undergraduate. He is also the recipient of the Korean government scholarship for study overseas (KGSPSO). Kwon is broadly interested in synthetic biology, protein engineering, and their application in biomedical fields such as developing novel living therapeutics.

 
Natalia Ubilla(PIBS Biological Chemistry)

Natalia Ubilla

(PIBS Biological Chemistry)

Natalia is from Southern California. She graduated from the University of California, Santa Cruz with a bachelor's in Biochemistry and Molecular Biology. As an undergraduate, she investigated how glycosylation affected the prion protein's ability to regulate itself and maintain its proper fold. During her gap year, she did a postbac at the Fred Hutchinson Cancer Research Center where she elucidated a series of structures from an engineered homing endonuclease in order to understand how novel DNA recognition specificity can be achieved. Natalia is broadly interested in using structural biology tools to better understand the functionality of proteins and the role encapsulin systems play in pathogenicity and virulence.

 

Visiting Students

Sania Mancer, MS

Sania is from France and graduated with a BS in Biochemistry and a MS in Quantitative Biology from the University of Montpellier, France. She completed her Honors thesis at the University of Michigan in the Bardwell lab, characterizing the structure and function of enzymes enhanced by directed evolution. She is broadly interested in the structural biology of proteins to understand their function in enzymatic activity or self-assembly.

 

Rotation Students

Undergraduate Students

Alumni

Jesse Jones (Postdoc)

Tae Heo (Undergraduate student, MCDB)

Jack Guo (Undergraduate student, MCDB)

William Myers (Rotation student, Biological Chemistry)

Carmen Castillo (Rotation student, Biological Chemistry)

Ryan Torres (Rotation student, ChemBio)

Casandra Sandoval (Rotation student, ChemBio)

Michael Cadigan (Rotation student, CMB)

Chase Lindeboom (Rotation student, Biological Chemistry)

Yun Zhang (Rotation student, Biological Chemistry)

Nien-Chi Lee (M.Sc. student, BME)

Ajitha Cristie-David (Postdoc)

Makhoul Cassis (Undergraduate student, BME)